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Writer's pictureTeresa Rodríguez

The Ketogenic Diet and Your Gut Microbiota: How They Work Together for Better Health


When we think of the ketogenic (keto) diet, the focus often lands on weight loss and metabolic health. But there's a hidden thing in this story—your gut microbiota.

These trillions of microorganisms living in your digestive tract play a huge role in your health, the keto diet can be a powerful tool in enhancing gut health. Whether managing a chronic condition or just looking to boost your well-being, the ketogenic diet could be the key to unlocking a healthier gut.



The Power of Your Microbiota

Your gut microbiota helps digestion, supports immune function, and influences mood and brain health. A healthy balance of these microorganisms is essential for keeping inflammation low and protecting against diseases like obesity, type 2 diabetes, and inflammatory bowel disease (IBD).

But how does a keto diet, which focuses on high fat, moderate protein, and very low carbohydrates, affect this delicate balance?



The Role of Akkermansia Muciniphila in Gut Health


One of the key players in gut health is a bacteria called Akkermansia Muciniphila. This bacteria is associated with a healthy gut lining and reduced inflammation, and it’s been found in higher numbers in people following specific dietary patterns, including the ketogenic diet. Studies, such as those discussed in the reference Rational Consideration of Akkermansia muciniphila Targeting Intestinal Health, show that the keto diet increases the abundance of this beneficial bacteria.


What makes Akkermansia Muciniphila so important?

  1. Strengthens the gut barrier: It helps maintain the mucous lining that protects your gut wall, reducing the risk of harmful substances passing into the bloodstream.


  2. Reduces inflammation: By promoting a healthy gut environment, A. Muciniphila may reduce chronic inflammation, which is linked to many diseases, including metabolic syndrome and obesity.


  3. Improves metabolic health: Research has shown that people with higher levels of A. Muciniphila tends to have better glucose metabolism, making it a key factor in reversing insulin resistance—a major benefit for people with type 2 diabetes or prediabetes.


How Does the Ketogenic Diet Support Gut Health?

The ketogenic diet, which is high in fats and low in carbohydrates, doesn’t just change how your body burns fuel—it also alters your gut microbiota composition. Here’s how:


  1. Increases A. Muciniphila: Studies show that following a ketogenic diet or even fasting can boost the number of A. Muciniphila in your gut. By increasing this beneficial bacteria, the keto diet strengthens the intestinal barrier and helps reduce inflammation, a win for overall gut health.


  2. Reduces Harmful Inflammation: Inflammatory bowel conditions like colitis may be eased by the ketogenic diet. According to one study, the diet reduces harmful immune cells in the gut by altering the microbiome. As inflammation is reduced, symptoms of gut discomfort and disease can improve.


  3. Balances Gut Microbiota: Shifting to a keto diet can help restore balance in the gut by promoting beneficial bacteria while reducing harmful ones. This helps prevent the overgrowth of harmful microbes that can lead to digestive disorders or worsen metabolic health issues.


Metabolic Health: A well-balanced gut microbiota also plays a role in regulating metabolism. The ketogenic diet, in boosting good bacteria like A. Muciniphila, may help improve insulin sensitivity, reduce body fat, and lower the risk of metabolic diseases like type 2 diabetes.



References:

  1. Wu X, Unno T, Kang S, Park S. A Korean-Style Balanced Diet Has a Potential Connection with Ruminococcaceae Enterotype and Reduction of Metabolic Syndrome Incidence in Korean Adults. Nutrients. 2021;13:495.https://www.mdpi.com/2072-6643/13/2/495

  2. Li L, et al. The effects of daily fasting hours on shaping gut microbiota in mice. BMC Microbiol. 2020;20:65. https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-020-01754-2

  3. Kong C, et al. Ketogenic diet alleviates colitis by reduction of colonic group 3 innate lymphoid cells through altering gut microbiome. Signal Transduct. Target. Ther. 2021;6:154. https://www.nature.com/articles/s41392-021-00549-9

  4. Plovier H, et al. A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med. 2017;23(1):107-113. https://www.nature.com/articles/nm.4236









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